ENNIS — State Highway 34 in Ennis was shut down for at least four hours in both directions Friday morning near Lone Oak Road, following a crash involving an Ennis ISD school bus and pickup truck.

The crash was called into the Ellis County Sheriff's Office at 7:26 a.m. when the Ennis ISD school bus and pickup truck collided.

The driver of the pickup had severe injuries and was been taken by ambulance to a Dallas hospital, and three Ennis ISD students as well as the bus driver were taken to Ennis Regional Medical Center for minor injuries, said James Colunga, the Texas Department of Public Safety spokesperson. The children were taken by ambulance and a private vehicle took the bus driver to the hospital.

An update on the conditions of all five injured was not available by 10 a.m. press time Saturday.

"An Ennis ISD school bus carrying three secondary students was involved in a collision this morning on HWY 34 and Novy Rd. All three students are being treated for minor injuries. All parents have been contacted," stated Art Del Barrio, Ennis ISD Communications Director, in a press release.

He added both the Ennis ISD superintendent and assistant superintendent went to the hospital shortly after the wreck to visit with the students.

Dense fog has also caused three other separate accidents, involving multiple vehicles, following the initial accident.

"The highway will be shut down for hours," Colunga said Friday morning.

The cause of initial accident was still under investigation as of press time, and it's unclear whether others were injured from the other three accidents.

This story is developing. Check back for more.