Plaza Medical Center of Fort Worth announced today Syed Nayyar Shah, M.D. performed its first patient implant in the RESPOND CRT clinical trial sponsored by Sorin Group. Plaza Medical Center is one of 60 U.S. hospitals, the only hospital in Tarrant County and the second in Texas, to participate in the trial evaluating the innovative SonR cardiac resynchronization therapy (CRT) system in patients with advanced heart failure. The RESPOND CRT study is a multi-center, randomized, two-arm, double-blinded, prospective trial that will enroll more than 1,000 patients worldwide.

A 73-year old male from Granbury, Texas was the first patient at Plaza Medical Center to receive the SonR CRT optimization system. He suffers from an advanced form of heart failure, a progressive condition in which the heart's muscle becomes weakened and doesn’t pump blood normally to supply the body's needs. 

“CRT to restore the heart’s coordinated pumping action has become an established treatment in combination with medical management for many patients with moderate to severe heart failure, but there is a significant percentage of patients who don’t respond to CRT,” said Syed Nayyar Shah, M.D., electrophysiologist with The Heart Center of North Texas. “I’m enthusiastic to study the SonR CRT optimization system, which offers first-of-its kind features to automatically adjust therapy to the patient’s activity with the goal of improving response to CRT, which may improve heart failure symptoms and reduce heart failure hospitalizations. In my view, this implantable medical technology may represent one of the best innovations in CRT in years.” 

About CRT Therapy

Cardiac resynchronization therapy delivers timely electrical pulses to the chambers of the heart. This allows the heart to beat in a more coordinated and synchronized manner, and thus more effectively. Studies have shown that around one-third of patients with advanced heart failure do not effectively respond to CRT1,2. 

The SonR CRT optimization system is under investigation in the United States and has not been approved by the U.S. Food and Drug Administration (FDA). 

For more information about the RESPOND CRT Clinical Trial, see 

About Plaza Medical Center of Fort Worth and North Texas Division of HCA Hospitals

Plaza Medical Center of Fort Worth, one of the 12 North Texas Division of HCA hospitals, was established in 1974. Located in the heart of the medical district, Plaza Medical Center is a 320-bed facility offering comprehensive diagnostic and treatment services. The hospital serves as a tertiary referral center not only for Tarrant County, but also numerous counties within a 90-mile radius, and offers cutting-edge diagnostic treatment services in a wide range of specialties and subspecialties, including Cardiac Care, Neurosciences, Oncology, Orthopedics and Specialty Surgery. For more information on Plaza Medical Center of Fort Worth, please visit For more information on the North Texas Division of HCA Hospitals, please visit